U.S., May 23 -- ClinicalTrials.gov registry received information related to the study (NCT06984510) titled 'Accelerated Biological Aging is Associated With Increased Risk of T2DM in the MASLD Population' on May 11.
Brief Summary: The association between biological aging and type 2 diabetes mellitus (T2DM) incidence in individuals with and without metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear.We assessed biological age by calculating phenotypic age (PhenoAge), Klemera-Doubal method (KDMAge), and homeostatic dysregulation (HDAge). To examine the association of biological ageing with the risk of T2DM, cox regression models were conducted. Furthermore, we applied survival analysis, restricted cubic spline mod...