Clinical Trial: A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

U.S., Aug. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07140913) titled 'A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine' on Aug. 21.

Brief Summary: The purpose of this study is to evaluate the efficacy and safety of adjunctive KarXT for the treatment of mania in participants with Bipolar-I Disorder.

Study Start Date: Sept. 05

Study Type: INTERVENTIONAL

Condition: Mania Bipolar Disorder

Intervention: DRUG: Xanomeline/Trospium Chloride

Specified dose on specified days

DRUG: Lithium

Specified dose on specified days

DRUG: Valproate

Specified...