U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT06890637) titled 'A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients with Crohn Disease on Advanced Therapies' on March 03.
Brief Summary: Advanced therapies including biologics and small molecules target specific inflammatory pathways. IBD's multifactorial etiology means that blocking a single pathway may not be sufficient for all patients. Even when combination of advanced therapies are used, the incremental benefits often diminish, reflecting the therapeutic ceiling. Furthermore, safety concerns also limit the potential to push beyond this ceiling. Increasing the dose or adding more immunosuppre...