U.S., July 3 -- ClinicalTrials.gov registry received information related to the study (NCT07047144) titled 'A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy' on April 16.
Brief Summary: This double-blind, Phase 2, multiple-dose study will be conducted to evaluate the PK/PD, efficacy, safety, and tolerability of apitegromab in subjects <2 years old with 5q autosomal recessive SMA who have delayed motor milestones for their age attributed to SMA at the discretion of the Investigator or a Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP-INTEND) score <55.
Study Start Date: Sept., 2025
Study Type: INTERVENTIONAL
Condition:
Spinal Muscular At...