U.S., July 11 -- ClinicalTrials.gov registry received information related to the study (NCT07058974) titled 'A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation' on July 01.

Brief Summary: This is a study assessing the feasibility of performing an anti-aging intervention which is a combination of an exercise regimen, spermidine supplementation, and either rapamycin or lamivudine.

Study Start Date: July, 2025

Study Type: INTERVENTIONAL

Condition: Smokers Former Smokers

Intervention: DRUG: lamivudine

Lamivudine (Epivir) is a drug used typically to treat HIV and Hepatitis B Virus (HBV). It has not been studied when given in combination with spermidine.

DRUG: rapamycin

Rapamycin (Rapamune, Sirolimus) is an FDA-...