Clinical Trial: A Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GNS-3545 in Healthy Participants

U.S., Nov. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07225296) titled 'A Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GNS-3545 in Healthy Participants' on Oct. 28.

Brief Summary: This is a randomized, double-blind, placebo-controlled Phase 1 study of SAD (Part 1) and MAD (Part 2) of orally administered GNS-3545 in healthy adult subjects. The food effect will be assessed in one cohort in Part 1.

Study Start Date: Nov. 12

Study Type: INTERVENTIONAL

Condition: Idiopathic Pulmonary Fibrosis

Intervention: DRUG: GNS-3545

GNS-3545 will be administered as oral tablets at assigned dose levels to six of the eight participants within...