U.S., May 1 -- ClinicalTrials.gov registry received information related to the study (NCT06951503) titled 'A Phase III, Randomized, Controlled and Multi-center Study of AK112 and Chemotherapy in First-line Metastatic Colorectal Cancer' on April 23.

Brief Summary: This trial is a Phase III study. The purpose of this study is to evaluate the efficacy and safety of AK112 and chemotherapy versus bevacizumab and chemotherapy for the first-line treatment of metastatic colorectal cancer.

Study Start Date: May 09

Study Type: INTERVENTIONAL

Condition: Colorectal Adenocarcinoma

Intervention: DRUG: AK112

iv, q2w

DRUG: Oxaliplatin

iv, q2w

DRUG: Irinotecan

iv, q2w

DRUG: Leucovorin and 5-FU

iv, q2w

DRUG: Bevacizumab

iv, q2w

Recruitment S...