U.S., March 6 -- ClinicalTrials.gov registry received information related to the study (NCT06858657) titled 'A Phase I Study to Assess the Safety,Tolerability, PK, PD, and Food Effect of HSK44459 in Healthy Subjects' on Aug. 15, 2024.

Brief Summary: This is a Phase I, randomized, subject-blinded, placebo controlled study to assess the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD),and food effect (FE) of HSK44459 following (1) a single ascending dose (part 1), (2) 10 days of multiple ascending dose (part 2), and (3) a single dose two-period crossover FE cohort.

Study Start Date: Aug. 17, 2024

Study Type: INTERVENTIONAL

Condition: Healthy

Intervention: DRUG: HSK44459

Dose 1 to Dose 5

DRUG: placebo

dose 1 to dose 5...