U.S., July 26 -- ClinicalTrials.gov registry received information related to the study (NCT07087262) titled 'A Phase I Study of SNH-119014 in Healthy Volunteers' on July 16.
Brief Summary: SNH-119014 is an oral small-molecule agonist of pyruvate kinase red blood cell isozyme (PKR) being developed for the treatment of hemolytic anemias. This initial study will characterize the safety, tolerability and the pharmacokinetics/pharmacodynamics (PK/PD) of a single ascending dose and multiple ascending doses of SNH-119014 in the context of Phase 1 studies in healthy volunteers. The effects of food on the absorption of SNH-119014 will also be evaluated in healthy volunteers.
Study Start Date: June 27
Study Type: INTERVENTIONAL
Condition:
Hemogl...