Clinical Trial: A Phase 1, Study of CD4-Targeted Chimeric Antigen Receptor T-Cells (CD4- CAR-T) in Subjects With Relapsed or Refractory T-Cell Lymphoma

U.S., Jan. 16 -- ClinicalTrials.gov registry received information related to the study (NCT04712864) titled 'A Phase 1, Study of CD4-Targeted Chimeric Antigen Receptor T-Cells (CD4- CAR-T) in Subjects With Relapsed or Refractory T-Cell Lymphoma' on Dec. 1, 2020.

Brief Summary: This is a Phase 1, first-in-human (FIH), open-label, multicenter, study of LB1901 administered to adult subjects with histologically confirmed CD4+ relapsed or refractory Peripheral T-cell lymphoma (PTCL) (PTCL not otherwise specified [PTCL-NOS] and angioimmunoblastic [AITL]), or relapsed or refractory cutaneous T-cell lymphoma (CTCL) (Sezary syndrome [SS] and mycosis fungoides [MF]).

Study Type: Interventional

Condition: * T-Cell Lymphoma

* Peripheral T-Cell Lymp...