U.S., Feb. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07417137) titled 'A Natural History Study of Angelman Syndrome' on Feb. 11.

Brief Summary: The goal of this observational study is to learn about the natural progression of Angelman syndrome (AS) in children and adults with a confirmed genetic diagnosis of AS. The main questions it aims to answer are:

* How do developmental skills, such as communication, motor abilities, and adaptive behaviors, change over a 1-year period in people with AS?

* Are there specific patterns in brain activity or sleep that are associated with changes in AS symptoms over time?

Participants will:

* Visit the study site 5 times over 1 year (approximately every 3 months) ...