U.S., Nov. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07232095) titled '7-Day Vonoprazan, High-Dose Amoxicillin, and Bismuth Therapy' on Nov. 14.
Brief Summary: The 2024 American College of Gastroenterology (ACG) Clinical Guideline recommends a 14-day vonoprazan-amoxicillin (VA) regimen, consisting of vonoprazan 20 mg twice daily with amoxicillin 1000 mg three times daily, as a first-line treatment for Helicobacter pylori (H. pylori) infection.
Our previous study on regimen optimization showed that vonoprazan 20 mg twice daily combined with amoxicillin 1 g three times daily or 750 mg four times daily for 10 days achieved satisfactory eradication rates exceeding 90%, with no significant difference betwe...