Clinical Trial: " Development of Primary Cultures of Diaphragmatic Myoblasts for Basic Research Purposes "

U.S., Feb. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07380308) titled '" Development of Primary Cultures of Diaphragmatic Myoblasts for Basic Research Purposes "' on Jan. 14.

Brief Summary: Neuromuscular diseases (NMDs) affecting motor neurons (MN) induce progressive muscle denervation, and become fatal when respiratory muscles e.g. the diaphragm are affected and can no longer contract. In some cases, such as Charcot's disease (Amyotrophic lateral sclerosis-ALS), there is no cure and patients die due to respiratory failure few years after diagnosis. Investigations on NMD-induced alterations of respiratory muscles in humans are limited notably by the absence of available in vitro model based on cell cult...