India, Sept. 17 -- image credit- shutterstock

Wadhwani School of Data Science and AI(WSAI), IIT Madras and ICMR-National Institute for Research in Reproductive and Child Health (ICMR-NIRRCH) researchers have developed a one-of-a-kind approach to fight fungal pathogen called 'Candida albicans' (CAL).

This multidisciplinary approach employed an integrated systems biology approach - combining large-scale computational modelling and experimental validation - to identify unknown critical metabolic vulnerabilities inC.albicans.It is the primary cause of Systemic Candidiasis, a major global health threat with a high mortality rate up to 63.6% in severe cases.

The rise of drug-resistant strains and lack of new antifungal drugs underline the ur...