Singapore, June 1 -- As the field shifts toward safer and more efficient gene delivery methods, PlasmidFactory's proprietary technology for producing non-synthetic minicircle DNA is gaining rapid attention across academia and industry.

Minicircle DNA has emerged as a next-generation gene vector with clear advantages over conventional plasmids. Lacking bacterial backbone sequences such as antibiotic resistance genes, minicircles are smaller, show reduced immunogenicity, and exhibit significantly enhanced gene expression. Their compact size allows greater cargo capacity and makes them ideal for sensitive applications in gene therapy, vaccine development, and cellular therapies like CAR-T.

Unlike traditional plasmids, minicircles consist p...