Washington, July 31 -- : A model using simple changes in microbe growth curves could predict how drug resistance evolves in response to different antibiotic combinations, doses, and sequences.
Scientists have proposed a modelling framework that could predict how antibiotic resistance will evolve in response to different treatment combinations, according to a study published in the journal eLife.
The research could help doctors optimise the choice, timing, dose, and sequence of antibiotics used to treat common infections, helping to halt the growing threat of antibiotic resistance to modern medicine.
"Drug combinations are a particularly promising approach for slowing resistance, but the evolutionary impacts of combination therapy remain ...