US Patent Issued to ZHEJIANG UNIVERSITY on Feb. 3 for "Chimeric antigen receptor, macrophage expressing same, method for adjusting macrophage polarization, and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,540,182, issued on Feb. 3, was assigned to ZHEJIANG UNIVERSITY (Hangzhou, China).

"Chimeric antigen receptor, macrophage expressing same, method for adjusting macrophage polarization, and use thereof" was invented by Jin Zhang (Hangzhou, China), Lin Tian (Hangzhou, China) and Anhua Lei (Hangzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are a chimeric antigen receptor, a macrophage expressing same, a method for adjusting macrophage polarization, and the use thereof. The intracellular domain of the chimeric antigen receptor contains an IFN-Gamma receptor, and the macrophage expressing the chimeric antigen receptor can maintain an M1 t...