US Patent Issued to ZHEJIANG UNIVERSITY on April 15 for "1,2-bis(diphenylphosphinoalkylamido)-1,2-disubstituted ethane, and its synthesis and application" (Chinese Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,750, issued on April 15, was assigned to ZHEJIANG UNIVERSITY (Zhejiang, China).

"1,2-bis(diphenylphosphinoalkylamido)-1,2-disubstituted ethane, and its synthesis and application" was invented by Shengming Ma (Zhejiang, China) and Yuchen Zhang (Zhejiang, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the design and synthesis of a class of novel chiral phosphine ligand, 1,2-bis(diphenylphosphinoalkylamido)-1,2-disubstituted ethane, and use in asymmetric catalytic reactions, such as asymmetric catalytic synthesis of pyrazoline-5-one with a chiral quaternary carbon center, i.e., highly enantioselective synthesis of ...