US Patent Issued to Zhejiang Huahai Pharmaceutical, Zhejiang Huahai LiCheng Pharmaceutical on March 25 for "Method for preparing voriconazole and intermediate thereof" (Chinese Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,330, issued on March 25, was assigned to Zhejiang Huahai Pharmaceutical Co. Ltd. (Xunqiao, China) and Zhejiang Huahai LiCheng Pharmaceutical Co. Ltd. (Xunqiao, China).

"Method for preparing voriconazole and intermediate thereof" was invented by Wenxiang Zhou (Xunqiao, China), Wenfeng Huang (Xunqiao, China) and Jiaxing Hu (Xunqiao, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is a method for preparing voriconazole and an intermediate thereof. In the method, a voriconazole condensate isomer is reacted as a starting material in the presence of an acid to obtain 4-chloro-6-ethyl-5-fluoropyrimidine and 2',4'-difluoro-2-[1-(1H-1,2,4-tri...