US Patent Issued to ZAKLADY FARMACEUTYCZNE POLPHARMA on Feb. 4 for "Pharmaceutical intermediate" (Polish Inventors)

ALEXANDRIA, Va., Feb. 5 -- United States Patent no. 12,215,081, issued on Feb. 4, was assigned to ZAKLADY FARMACEUTYCZNE POLPHARMA S.A. (Starogard Gdanski, Poland).

"Pharmaceutical intermediate" was invented by Adam Haluszczuk (Gdansk, Poland) and Dorota Pogoda (Syrynia, Poland).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to 4-(4-fluorobenzylamino)-1-methylpiperidine trihydrate and a process for the preparation of 4-(4-fluorobenzylamino)-1-methylpiperidine trihydrate comprising treating 4-(4-fluorobenzylamino)-1-methylpiperidine with water.The invention also relates to a process for the preparation of pimavanserin comprising reacting 4-(4-fluorobenzylamino)-1-methylpiperidine trihydr...