ALEXANDRIA, Va., June 16 -- United States Patent no. 12,304,881, issued on May 20, was assigned to YU-JET Co. LTD (Taipei, Taiwan).
"Trientine tetrahydrochloride and a method of preparation and a pharmaceutical composition thereof" was invented by Cherng-Yih Perng (Hsinchu County, Taiwan), Ming-Ren Liang (Taoyuan, Taiwan), Yu-Chen Lin (Zhubei, Taiwan) and Tai-Yun Feng (Taoyuan, Taiwan).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method of preparation of trientine tetrahydrochloride crystals in which an anti-solvent at a feeding temperature is added into a trientine tetrahydrochloride solution and stirred for crystallization wherein the feeding temperature ranges from 50deg C. to 75deg C. and the anti-sol...