ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,413, issued on Jan. 13, was assigned to YEDITEPE UNIVERSITESI (Istanbul).
"Molecular basis of fatty liver inhibition by sodium borates" was invented by Fikrettin Sahin (Istanbul), Emre Cebeci (Istanbul) and Huseyin Abdik (Istanbul).
According to the abstract* released by the U.S. Patent & Trademark Office: "Sodium borates are provided as the sole active ingredient to prevent and/or treat fatty liver. In addition, the sodium borates reduce the expression levels of ADIPOR2, PRKAG2, IRS1, PIK3R1, NFKB1, MAP3K11, BID, CYCS, BAX, CASP3 and TGFB1 genes in the non-alcoholic fatty liver pathway and thereby to prevent and/or treat fatty liver by inhibiting the functioning of the non-alcoh...