ALEXANDRIA, Va., June 19 -- United States Patent no. 12,332,246, issued on June 17, was assigned to YEDA RESEARCH AND DEVELOPMENT Co. LTD. (Rehovot, Israel).

"Quinoline based cyanine dye turn-on fluorescent probes and methods of use thereof" was invented by David Margulies (Rehovot, Israel), Leila Motiei (Rehovot, Israel), Pragati Prasad (Rehovot, Israel), Tom Granot (Rehovot, Israel) and Ohad Suss (Rehovot, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention is directed to a turn-on fluorescent probe, wherein said probe comprises a quinoline based cyanine dye derivative (QBC) and a specific protein binder covalently attached thereto directly or via a linker. This invention is further direct...