US Patent Issued to YALE UNIVERSITY on Sept. 23 for "Methods and compositions for the treatment of amyloid-related disorders" (Connecticut Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,419,905, issued on Sept. 23, was assigned to YALE UNIVERSITY (New Haven, Conn.).

"Methods and compositions for the treatment of amyloid-related disorders" was invented by Stephen M. Strittmatter (Durham, Conn.), Erik Christian Gunther (Branford, Conn.) and Levi M. Smith (Branford, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides polymeric compounds that inhibit binding of an amyloid-Beta-oligomer to cellular prion protein, methods for identifying such compounds, and their therapeutic use. In particular, the present disclosure provides a collection of anionic polymers and methods of using these compounds to treat amyloid-rela...