US Patent Issued to YALE UNIVERSITY on May 27 for "Reprogramming urokinase into an antibody-recruiting anticancer agent" (Massachusetts, Connecticut Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,621, issued on May 27, was assigned to YALE UNIVERSITY (New Haven, Conn.).

"Reprogramming urokinase into an antibody-recruiting anticancer agent" was invented by David A. Spiegel (New Haven, Conn.) and Charles E. Jakobsche (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to chimeric (preferably, bifunctional) compounds, compositions comprising those compounds and methods of treating cancer in a patient or subject, especially including metastatic cancer where cancer cells exhibit overexpression (heightened expression) of cell surface urokinase-type plasminogen activator receptor (urokinase receptor) compa...