US Patent Issued to YALE UNIVERSITY on April 15 for "Methods for treatment of cancer using chikungunya-VSV chimeric virus" (Connecticut Inventor)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,274,724, issued on April 15, was assigned to YALE UNIVERSITY (New Haven, Conn.).

"Methods for treatment of cancer using chikungunya-VSV chimeric virus" was invented by Anthony N. van den Pol (Branford, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Chimeric viruses having a vesicular stomatitis virus (VSV) background where the VSV G protein is supplemented or replaced with an alphavirus glycoprotein(s), or a functional fragment(s) thereof, are provided. A preferred alphavirus is Chikungunya virus. In particular embodiments, the glycoprotein(s) is or includes E3, E2, K6, and E1 proteins of an alphavirus, preferably Chikungunya virus. Methods of usin...