ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,580, issued on Nov. 18, was assigned to XINGZHI COLLEGE ZHEJIANG NORMAL UNIVERSITY (Lanxi, China).

"One-step method for synthesizing amoxicillin from penicillin or salt thereof through enzyme catalysis" was invented by Zhonghua Yang (Jinhua, China) and Xiaoyan Yin (Jinhua, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "A one-step method for synthesizing amoxicillin from penicillin or a salt thereof through an enzyme catalysis is provided. Conventional amoxicillin production requires sequential use of distinct penicillin acylases for hydrolysis and synthesis steps, necessitating isolation of the intermediate 6-aminopenicillanic acid (6-APA) and...