US Patent Issued to Xilio Development, City of Hope on Aug. 12 for "Activatable masked anti-CTLA4 binding proteins" (California, Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,384,845, issued on Aug. 12, was assigned to Xilio Development Inc. (Waltham, Mass.) and City of Hope (Duarte, Calif.).

"Activatable masked anti-CTLA4 binding proteins" was invented by John C. Williams (Duarte, Calif.) and Margaret Karow (Waltham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides activatable masked anti-CTLA4 binding proteins (e.g., antibodies, bispecific antibodies, and chimeric receptors) and their use in treating and preventing cancer, as well as compositions and kits comprising the activatable masked anti-CTLA4 binding proteins."

The patent was filed on Dec. 26, 2019, under Application No. 17/417,239.

*For...