ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,849, issued on Sept. 16, was assigned to Xencor Inc. (Pasadena, Calif.).
"Heterodimeric proteins" was invented by Gregory Moore (Azusa, Calif.), Matthew Bernett (Monrovia, Calif.), Rumana Rashid (Arcadia, Calif.) and John Desjarlais (Pasadena, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "In one aspect, the present invention provides heterodimeric antibodies comprising a first monomer comprising a first heavy chain constant domain comprising a first variant Fc domain and a first antigen binding domain and a second monomer comprising a second heavy chain constant domain comprising a second variant Fc domain and a second antigen binding domai...