US Patent Issued to Xencor on Dec. 16 for "Methods and compositions for inhibiting CD32B expressing cells in IGG4-related diseases" (California Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,457, issued on Dec. 16, was assigned to Xencor Inc. (Pasadena, Calif.).

"Methods and compositions for inhibiting CD32B expressing cells in IGG4-related diseases" was invented by Seung Yup Chu (Cypress, Calif.), John R. Desjarlais (Pasadena, Calif.), Sher Bahadur Karki (Pomona, Calif.), Gregory Alan Lazar (Arcadia, Calif.), Gregory L. Moore (Monrovia, Calif.) and Igor Vostiar (Monrovia, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to immunoglobulins that bind FcGammaRIIb+ cells and coengage the antigen on the cell's surface and an FcGammaRIIb on the cell's surface, methods for their generation, and methods for u...