US Patent Issued to Wuhan YZY Biopharma on June 17 for "Modified Fc fragment, antibody comprising same, and application thereof" (Chinese Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,119, issued on June 17, was assigned to Wuhan YZY Biopharma Co. Ltd. (Wuhan, China).

"Modified Fc fragment, antibody comprising same, and application thereof" was invented by Jing Zhang (Wuhan, China), Lijuan Fang (Wuhan, China), Yongxiang Yan (Wuhan, China), Liang Zeng (Wuhan, China) and Pengfei Zhou (Wuhan, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to a modified Fc fragment, antibodies containing the same and the use thereof. The Fc fragment is derived from human IgG1, and the constant region CH2 domain of the Fc fragment contains multiple substitutions. Such substitution can significantly reduce the bindi...