US Patent Issued to Wisconsin Alumni Research Foundation on Oct. 7 for "Lineage reprogramming to induced cardiac progenitor cells (iCPC) by defined factors" (Wisconsin Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,313, issued on Oct. 7, was assigned to Wisconsin Alumni Research Foundation (Madison, Wis.).

"Lineage reprogramming to induced cardiac progenitor cells (iCPC) by defined factors" was invented by Timothy Joseph Kamp (Madison, Wis.) and Pratik Arvind Lalit (Madison, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Animal cells, notably adult fibroblasts, are advantageously reprogrammed in direct lineage reprogramming methods using defined factors to produce proliferative and multipotent induced cardiac progenitor cells (iCPC). The iCPC thus produced can be differentiated under suitable differentiation conditions to cardiac lineage cells including ca...