US Patent Issued to Wisconsin Alumni Research Foundation on Oct. 28 for "Derivation of human microglia from pluripotent stem cells" (Wisconsin, Texas Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,676, issued on Oct. 28, was assigned to Wisconsin Alumni Research Foundation (Madison, Wis.).

"Derivation of human microglia from pluripotent stem cells" was invented by James A. Thomson (Madison, Wis.), Nicholas E. Propson (Houston), Michael P. Schwartz (Madison, Wis.), Zhonggang Hou (Madison, Wis.), Gene I. Uenishi (Madison, Wis.), Igor I Slukvin (Verona, Wis.), William L. Murphy (Waunakee, Wis.) and Jue Zhang (Madison, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to methods for deriving human hematopoietic progenitors, primitive macrophages, and microglial cells from human pluripotent stem cells. In particular...