ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,453, issued on May 13, was assigned to Wisconsin Alumni Research Foundation (Madison, Wis.).
"Generation of norepinephrine neurons from human stem cells" was invented by Su-Chun Zhang (Waunakee, Wis.) and Yunlong Tao (Madison, Wis.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods for obtaining populations of norepinephrine (NE) neuronal progenitor cells and creating enriched populations of NE neurons are provided herein. Also provided herein are methods for obtaining genetically modified NE neurons expressing a NE sensor or a TH-reporter, and methods for using NE neurons obtained according to the methods of this disclosure."
The patent was fi...