ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,529,032, issued on Jan. 20, was assigned to Wisconsin Alumni Research Foundation (Madison, Wis.).
"Methods and culture substrates for controlled induction of biomimetic neural tissues comprising singular rosette structures" was invented by Randolph Scott Ashton (Madison, Wis.) and Gavin T. Knight (Coral Springs, Fla.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods, compositions, and kits for directed differentiation of human pluripotent stem cells, neuromesodermal progenitors, and neural stem cells into biomimetic neural tissues comprising one or more rosette structures. Preferably, the methods provided herein direct differen...