US Patent Issued to Wisconsin Alumni Research Foundation on Aug. 19 for "Sirtuin 6 protein deacylase (SIRT6) activators" (Wisconsin Inventors)

ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,390,447, issued on Aug. 19, was assigned to Wisconsin Alumni Research Foundation (Madison, Wis.).

"Sirtuin 6 protein deacylase (SIRT6) activators" was invented by John Matthew Denu (Madison, Wis.) and Weiping Tang (Madison, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides compounds according to Formula I and pharmaceutically acceptable salts thereof, as well as compositions including such compounds and a pharmaceutically acceptable carrier or excipient. Further provided are methods of inactivating SIRT6 with compounds of Formula I as well as compounds of Formula III, W2-R2-Y-R3, as described herein. In addition, the pr...