ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,557, issued on March 25, was assigned to Wisconsin Alumni Research Foundation (WARF) (Madison, Wis.) and The University of Tokyo (Tokyo).

"Humanized cell line" was invented by Yoshihiro Kawaoka (Middleton, Wis.), Kosuke Takada (Tokyo) and Masaki Imai (Kawasaki, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A mammalian or avian cell line that expresses high levels of human influenza virus receptors is provided. In one embodiment, the cell line supports human influenza virus, e.g., human A/H3 influenza virus, isolation and growth much more effectively than corresponding conventional (unmodified) cells or in corresponding human virus receptor-o...