US Patent Issued to WILLIAM MARSH RICE UNIVERSITY on Nov. 4 for "Synthesis of isoprenoids and derivatives" (California, Florida, Texas Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,234, issued on Nov. 4, was assigned to WILLIAM MARSH RICE UNIVERSITY (Houston).

"Synthesis of isoprenoids and derivatives" was invented by Ramon Gonzalez (Tampa, Fla.), James M. Clomburg (Houston) and Seokjung Cheong (Emeryville, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure generally relates to the use of enzyme combinations or recombinant microbes comprising same to make isoprenoid precursors, isoprenoids and derivatives thereof including prenylated aromatic compounds. Novel metabolic pathways exploiting Claisen, aldol, and acyloin condensations are used instead of the natural mevalonate (MVA) pathway or 1-deoxy-d-xylulose 5...