ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,350, issued on June 17, was assigned to William Marsh Rice University (Houston).

"Systems and methods for allele enrichment using multiplexed blocker displacement amplification" was invented by David Yu Zhang (Houston), Ping Song (Houston) and Xi Chen (Houston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are reagents and methods for simultaneously enriching many potential rare genetic variants at different genetic loci. The rare variants enriched can include single nucleotide polymorphisms (SNPs), single nucleotide variants, or small insertions and deletions. Embodiments of the invention include procedures for integration with down...