US Patent Issued to Whitehead Institute for Biomedical Research on Feb. 25 for "Regulation of transcription through CTCF loop anchors" (Massachusetts Inventors)

ALEXANDRIA, Va., Feb. 26 -- United States Patent no. 12,234,453, issued on Feb. 25, was assigned to Whitehead Institute for Biomedical Research (Cambridge, Mass.).

"Regulation of transcription through CTCF loop anchors" was invented by Jurian Schuijers (Somerville, Mass.), Abraham S. Weintraub (Cambridge, Mass.), John C. Manteiga (Boston) and Richard A. Young (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods of altering expression of a gene with a promoter region CTCF binding site. Also disclosed are compositions and methods useful for treating a disease or condition involving over-expression or under-expression of a gene with a promoter region CTCF binding site. Further disclosed ...