ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,863, issued on July 15, was assigned to WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (Sichuan, China).

"Nitrogen-containing derivative of substituted phenol hydroxy acid ester, and preparation and use thereof" was invented by Jun Yang (Sichuan, China), Jin Liu (Sichuan, China) and Weiyi Zhang (Sichuan, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "A nitrogen-containing derivative of substituted phenol hydroxyl acid ester is represented by formula (I). A salt of the compound of formula (I) has good water solubility, and in vivo, can rapidly and completely release substituted phenols having a pharmacological effect, which can improve the water solub...