US Patent Issued to Werewolf Therapeutics on Jan. 27 for "Activatable interleukin-2 polypeptides and methods of use thereof" (American, German Inventors)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,505, issued on Jan. 27, was assigned to Werewolf Therapeutics Inc. (Watertown, Mass.).

"Activatable interleukin-2 polypeptides and methods of use thereof" was invented by William Winston (West Newton, Mass.), Daniel Hicklin (Boston), Vinay Bhaskar (San Francisco), Luke Evnin (San Francisco), Patrick Baeuerle (Gauting, Germany), Jose Andres Salmeron Garcia (Acton, Mass.), Heather Brodkin (West Newton, Mass.) and Cynthia Seidel-Dugan (Belmont, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure features fusion proteins that are conditionally active variants of IL-2. In one aspect, the full-length polypeptides of the invention have redu...