ALEXANDRIA, Va., March 12 -- United States Patent no. 12,246,114, issued on March 11, was assigned to Washington University (St. Louis).

"Biomedical patches with spatially arranged fibers" was invented by Matthew R. MacEwan (St. Louis).

According to the abstract* released by the U.S. Patent & Trademark Office: "A three-dimensional electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The three-dimensional electrospun nanofiber scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is coupled to the first layer using a coupling process and includes a plurality of va...