US Patent Issued to Washington University on Dec. 9 for "Blood-based assay for diagnosing and treating based on site-specific tau phosphorylation" (Missouri Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,493,043, issued on Dec. 9, was assigned to Washington University (St. Louis).

"Blood-based assay for diagnosing and treating based on site-specific tau phosphorylation" was invented by Randall Bateman (St. Louis) and Nicolas Barthelemy (St. Louis).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues, using blood samples, to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventio...