US Patent Issued to Washington University, Whitehead Institute for Biomedical Research on July 29 for "Enhanced methods for inducing and maintaining naive human pluripotent stem cells" (Missouri Inventors)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,667, issued on July 29, was assigned to Washington University (St. Louis) and Whitehead Institute for Biomedical Research (Cambridge, Mass.).

"Enhanced methods for inducing and maintaining naive human pluripotent stem cells" was invented by Thorold Theunissen (St. Louis), Shafqat Khan (St. Louis) and Rudolf Jaenisch (St. Louis).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods and compositions for inducing, maintaining and/or passaging naive pluripotent stem cell. In some embodiments, the methods are performed in the absence of MEK inhibition which has been shown to result in genomic instability of naive pluripote...