US Patent Issued to Wake Forest University Health Sciences on June 3 for "Cytotoxic fluoropyrimidine polymers and methods of use thereof" (North Carolina Inventor)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,915, issued on June 3, was assigned to Wake Forest University Health Sciences (Winston-Salem, N.C.).

"Cytotoxic fluoropyrimidine polymers and methods of use thereof" was invented by William H. Gmeiner (Yadkinville, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Novel cytotoxic fluoropyrimidine polymers for treating cancer (e.g., colorectal cancer (CRC)) in a subject (e.g., a subject having cancer) are nucleic acid molecules including 5-fluoro-2'deoxyuridine monophosphate (FdUMP)[10] having a polyethylene glycol (PEG) spacer appended to the 5' terminus and a cytarabine (AraC) nucleotide appended to 3'termius. These novel cytotoxic fluoropyrimidin...