ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,586, issued on Oct. 14, was assigned to Vrije Universiteit Brussel (Brussels).
"Radiolabelled antibody fragments for use in treating cancer" was invented by Tony Lahoutte (Ganshoren, Belgium), Matthias D'Huyvetter (Antwerp, Belgium), Jens De Vos (Strombeek-Bever, Belgium) and Nick Devoogdt (Eppegem-Zemst, Belgium).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods, kits, and compositions for stratifying and treating subjects, e.g., subjects having cancer. In some examples, the methods involve use of a radiolabelled heavy chain variable domain derived from a heavy chain antibody (VHH), or a functional fragment thereof, as both ...