ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,558,416, issued on Feb. 24, was assigned to Vrije Universiteit Brussel (Brussels).
"Endothelium-specific nucleic acid regulatory elements and methods and use thereof" was invented by Marinee Chuah (Bierbeek, Belgium) and Thierry Vandendriessche (Bierbeek, Belgium).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides nucleic acid regulatory elements that are able to enhance endothelial cell-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The nucleic acid regulatory elements, methods ...