US Patent Issued to VIRONGY on March 25 for "Cofilin phosphorylation for quantifying CD4 T cell damage and predict CD4 T cell recovery from anti-retroviral therapy" (Virginia Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,259,388, issued on March 25, was assigned to VIRONGY LLC (Manassas, Va.).

"Cofilin phosphorylation for quantifying CD4 T cell damage and predict CD4 T cell recovery from anti-retroviral therapy" was invented by Yuntao Wu (Manassas, Va.), Hong Shang (Manassas, Va.) and Yajing Fu (Manassas, Va.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A major immune dysfunction persisting in chronic diseases such as HIV infection and cancer is the impairment of T cell motility and migration to tissues. Therapeutics such as antiretroviral therapy or cancer therapy frequently do not fully restore T cell motility for tissue migration and infiltration. Cofilin is an ac...