ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,677, issued on Oct. 14, was assigned to VIFOR (INTERNATIONAL) LTD. (St. Gallen, Switzerland).
"One step synthesis for alkyl 2-fluoroacrylates" was invented by Qingwu Jin (Bothell, Wash.) and Michael Whitacre (San Carlos, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A process is provided that results in an alkyl haloacrylate that is produced by reaction of a dialkyl or diaryl halomalonate with an aldehyde, preferably formalin or paraformaldehyde, and a base catalyst to produce an intermediate that is not isolated and is heated to produce the alkyl haloacrylate. This synthesis can be one pot, meaning it reacts in the same vessel and/or reacti...